Funding

Current Research Funding

Grant	Project	Description	PI	Duration
SU2C-CRUK Pediatric Cancer New Discoveries Challenge	Targeting R-loop stability in Ewing sarcoma	To determine the therapeutic utility of targeting R-loop stabilizing mechanisms in Ewing sarcoma.	Bishop	10/2020 – 09/2022
NIH/NCI R01 CA241554	Dysregulated transcription processes in Ewing sarcoma	To determine the consequences of dysregulated transcription regulation in Ewing sarcoma.	Bishop	05/2020 – 04/2025
CPRIT RP170345	UTHSCSA Cancer Research Training Program	Research Training Award supports for pre-doctoral, post-doctoral trainees, and summer (undergraduate) students, as part of a comprehensive training program covering all aspects cancer research.	Oyajobi, Colaborator: Bishop	12/01/16 – 11/20/21
The Andrew McDonough B+ Foundation #614252: Research Grant	Targeting RNA processing defects of Ewing sarcoma	To follow up on initial validations of a previously conducted RNAi screen that identified splicing components as synthetic lethal target in Ewing sarcoma. The aim is to then evaluate splicing inhibitors that have the same effect as RNAi depletion of splicing genes and if a therapeutic window exists that can that suggests these inhibitors can be used in the treatment of Ewing sarcoma.	Bishop	01/2019 – 12/2020
IIMS/GCCRI Pilot funds	Targeting the transcription dysregulation of Ewing sarcoma	To validate an RNAi screen for synthetic lethal viability in Ewing sarcoma to identify determinants of transcription regulation and therapeutic targets that can be used in the treatment of Ewing sarcoma.	Bishop	05/2017 – 04/2019 (NCE to 04/2020)
GCCRI pilot experiment support	Metabolomics in ATM inhibited cells	Isotope tracing metabolomics experiment in cells +/- ATM inhibitor for glucose and glutamine utilization.	Bishop	09/2019 – 08/2020
MERCK EMD Serano	Assessing the accumulation of R-loops in cancer as an indication of sensitivity to RNA splicing inhibition	To identify whether high R-loops indicate splicing defects in cancers and sensitivity to splicing inhibitors.	Bishop	10/2019 – 10/2021

Ongoing Fellowships to Trainees

Grant	Project	PI	Mentor	Duration
Greehey Graduate Predoctoral Fellowship Predoctoral Fellowship	Epigenetic changes in Ewing Sarcoma.	Miller	Bishop	09/2020 – 09/2021
Mays Cancer Center Fellowship Predoctoral Fellowship	Ewing Sarcoma relies on Endogenous Cysteine and Glutamine for Antioxidant Response.	Kanda	Bishop	08/2020 – 07/2022
CPRIT Training Grant RP170345 Predoctoral Fellowship	Evaluate replication stress in Ewing sarcoma.	Mukhopadhyay	Bishop	10/2020 – 09/2021
AACR-AstraZeneca START fellowship	Identifying Modifiers of PARP1 Inhibitor Sensitivity in BRCA-like Tumors	Gorthi	Bishop	08/2018 – 07/2021
CDMRP PRCRP Horizon Fellowship CA181177	Transcription, R-Loops, and RNA Splicing in Ewing Sarcoma	Lawrence	Bishop	08/2019 – 07/2021

Completed Research Funding

Grant	Project	PI	Duration
CPRIT RP150445: IIRACCA	Ewing’s sarcoma, a homologous recombination defective disease	Bishop	03/2015 – 02/2019 (NCE to 08/2019)
Najim Foundation and GCCRI funds Award	To conduct a siRNA viability screen in Ewing sarcoma cells to identify new targets for treatment.	Bishop	07/2015 – 06/2016
Hyundai Hope on Wheels Hope Grant Award	Homologous recombination defect in malignant myeloid diseases in children	Bishop	09/2012 – 08/2014
San Antonio Area Foundation 152711 Biomedical Research Grant	Targeting altered nucleotide pool to treat cancer cells	Bishop	05/2012 – 04/2013
NIH NCI 1R01CA179120	miRNAs: Safe and effective therapeutic adjuvants for treating drug resistant TNBC	Rao, Co-I: Bishop	02/2015 – 01/2020
NIH/NCI R01CA152063	Improving etoposide treatment of Ewing’s sarcoma	Bishop	09/2011 – 07/2016 (NCE to 07/2018)
Helen Freeborn Kerr Charitable Foundation Award	Identifying mechanisms involved in cancer development and novel means to prevent cancer forming	Bishop	09/2011 – 04/2012
Max and Minnie Tomerlin Voelcker Fund Young Investigator Award	Determining cisplatin survival factors to augment ovarian cancer treatment	Bishop	07/2010 – 06/2013
ACS RSG-10-049-01-DMC Research Grant	Integration of the Jun N-terminal Kinase and p53 signaling pathways	McEwan, Co-I: Bishop	01/2010 – 12/2013
NIH/NIEHS R15ES019128	Comparing and contrasting the biology of damage survival at a genomic level	Bishop	05/2010 – 10/2013
ACS 122295 Pilot	Using conditional mutants to investigate recombination	Bishop	08/2005 – 08/2006
NIH/NIEHS K22 ES-02-006	A screen for damage response using recombination	Bishop	09/2004 – 09/2007 (NCE to 05/2010)

Completed Fellowship Funding

Grant	PI	Mentor	Duration
NCATS TL1TR002647 Postdoctoral fellowship	Gorthi	Bishop and Chen	07/2018 – 06/2019
NCATS TL1TR002647 Predoctoral Training Fellowship	Lawrence	Bishop	07/2018 – 06/2020
NIH/NCI T32CA148724 Postdoctoral fellowship	Gorthi	Bishop and Chen	09/2015 – 08/2017
Greehey Graduate Predoctoral Fellowship	Sybouts	Bishop	09/2015 – 08/2016
CPRIT Training Grant Postdoctoral Fellowship	Romero	Bishop	09/2015 – 08/2016
DoD CDMRP BCRP Postdoctoral Fellowship	Zanotto-Filho	Bishop	12/2013 – 11/2016
Greehey Graduate Predoctoral Fellowship	Chavez-Santosco	Bishop	09/2013 – 08/2014
NIH/NCI T32CA148724 Predoctoral Fellowship	Tonapi	Bishop	07/2013 – 06/2015
CPRIT Training Grant Predoctoral Fellowship	Gorthi	Bishop	10/2012 – 09/2013
Greehey Graduate Predoctoral Fellowship	Gorthi	Bishop	09/2011 – 08/2012
DoD CDMRP BCRP BC093931 Predoctoral Fellowship	Karia	Bishop	01/2010 – 12/2012
NIH/NIA 5T32AG021890 Predoctoral Fellowship	Brown	Bishop	05/2007 – 04/2012
NIH/NIGMS F32 GM19147 Postdoctoral Fellowship	Bishop		07/1997 – 06/2000
Medical Research Council UK Predoctoral Fellowship	Bishop		09/1993 – 08/1996